Expeditious synthesis of Mosher amides using a solid supported carbodiimide

被引：11

作者：

Adamczyk, M

Fishpaugh, JR

机构：

[1] Abbott Laboratories, Abbott Park, IL 60064, 100 Abbott Park Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 40期

关键词：

D O I：

10.1016/0040-4039(96)01617-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel method of Mosher amide synthesis using a solid supported carbodiimide in CDCl3 is described. Estimation of optical purity can be promptly achieved by direct NMR analysis of the reaction solvent. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：7171 / 7172

页数：2

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