Rapid and convergent assembly of the polycyclic framework assigned to the cytotoxic marine alkaloid halitulin

被引:21
作者
Banwell, MG [1 ]
Bray, AM
Edwards, AJ
Wong, DJ
机构
[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia
[2] Mimotopes Pty Ltd, Melbourne, Vic 3169, Australia
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2002年 / 11期
关键词
D O I
10.1039/b111401h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Compound 3, representing the tetra-O-methyl ether derivative of structure, 1, assigned to the cytotoxic marine alkaloid halitulin, has been assembled in a convergent manner from the readily available building blocks 5, 6 and 11.
引用
收藏
页码:1340 / 1343
页数:4
相关论文
共 19 条
  • [11] PALLADIUM(O)-CATALYZED CROSS-COUPLING REACTION OF ALKOXYDIBORON WITH HALOARENES - A DIRECT PROCEDURE FOR ARYLBORONIC ESTERS
    ISHIYAMA, T
    MURATA, M
    MIYAURA, N
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (23) : 7508 - 7510
  • [12] Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis
    Kashman, Y
    Koren-Goldshlager, G
    Gravalos, G
    Schleyer, M
    [J]. TETRAHEDRON LETTERS, 1999, 40 (05) : 997 - 1000
  • [13] KASHMAN Y, Patent No. 0020411
  • [14] Haliclorensin, a novel diamino alkaloid from the marine sponge Haliclona tulearensis
    Koren-Goldshlager, G
    Kashman, Y
    Schleyer, M
    [J]. JOURNAL OF NATURAL PRODUCTS, 1998, 61 (02): : 282 - 284
  • [15] Palladium-catalyzed borylation of aryl halides or triflates with dialkoxyborane: A novel and facile synthetic route to arylboronates
    Murata, M
    Oyama, T
    Watanabe, S
    Masuda, Y
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (01) : 164 - 168
  • [16] Processing of X-ray diffraction data collected in oscillation mode
    Otwinowski, Z
    Minor, W
    [J]. MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 : 307 - 326
  • [17] Spek A., 1990, ACTA CRYSTALLOGR, V46
  • [18] TRECOURT F, 1995, SYNTHESIS-STUTTGART, P1159
  • [19] WATKIN DJ, 1966, CRYSTALS