Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

被引：1354

作者：

Chen, Wansong ^{[1
,2
]}

Ouyang, Jiang ^{[2
]}

Liu, Hong ^{[1
,3
]}

Chen, Min ^{[2
]}

Zeng, Ke ^{[2
]}

Sheng, Jianping ^{[2
]}

Liu, Zhenjun ^{[2
]}

Han, Yajing ^{[2
]}

Wang, Liqiang ^{[2
]}

Li, Juan ^{[2
]}

Deng, Liu ^{[2
]}

Liu, You-Nian ^{[1
,2
]}

Guo, Shaojun ^{[4
,5
]}

机构：

[1] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China

[2] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China

[3] Cent South Univ, Aier Ophthalm Coll, Changsha 410083, Hunan, Peoples R China

[4] Peking Univ, Coll Engn, Dept Mat Sci & Engn, Beijing 100871, Peoples R China

[5] Peking Univ, Coll Engn, BIC ESAT, Beijing 100871, Peoples R China

来源：

ADVANCED MATERIALS | 2017年 / 29卷 / 05期

基金：

中国国家自然科学基金;

关键词：

PHOTODYNAMIC THERAPY; PHOTOTHERMAL THERAPY; ANTICANCER DRUG; GRAPHENE OXIDE; NANOPARTICLES; PLATFORM; ACCUMULATION; HYPERTHERMIA; NANOPLATFORM; CHEMOTHERAPY;

D O I：

10.1002/adma.201603864

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A black phosphorus (BP)-based drug delivery system for synergistic photodynamic/ photothermal/chemotherapy of cancer is constructed. As a 2D nanosheet, BP shows super high drug loading capacity and pH-/photoresponsive drug release. The intrinsic photothermal and photodynamic effects of BP enhance the antitumor activities. The synergistic photo-dynamic/photothermal/chemotherapy makes BP-based drug delivery system a multifunctional nanomedicine platform.

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页数：7

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