Application of gene expression profiling to cardiovascular disease

被引:30
作者
Henriksen, PA [1 ]
Kotelevtsev, Y [1 ]
机构
[1] Univ Edinburgh, Div Biomed Sci, Edinburgh EH8 9XD, Midlothian, Scotland
基金
英国惠康基金;
关键词
gene expression; sequence (DNA/RNA/prot);
D O I
10.1016/S0008-6363(01)00516-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The number of cardiovascular publications featuring gene expression profiling technologies is growing rapidly. This article introduces four profiling techniques; serial analysis of gene expression, differential display, subtractive hybridisation and DNA microarrays. Illustrations of their application towards cardiovascular research are given and their potential for gene discovery and improving our understanding of gene function is discussed. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:16 / 24
页数:9
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