Convenient approaches to synthesis of furanoid sugar-aza-crown ethers from C-ribosyl azido aldehyde via a reductive amination/amidation

被引：11

作者：

Hsieh, Yu-Chi ^{[1
]}

Chir, Jiun-Ly ^{[2
]}

Zou, Wei ^{[3
]}

Wu, Hsiu-Han ^{[1
]}

Wu, An-Tai ^{[1
]}

机构：

[1] Natl Changhua Univ Educ, Dept Chem, Changhua 50058, Taiwan

[2] Acad Sinica, Biotechnol Ctr So Taiwan, Sinshih Township 744, Tainan County, Taiwan

[3] Natl Res Council Canada, Inst Biol Sci, Ottawa, ON K1A 0R6, Canada

来源：

CARBOHYDRATE RESEARCH | 2009年 / 344卷 / 08期

关键词：

Furanoid; Sugar-aza-crown ether; Amination; Amidation; OLIGOSACCHARIDE MIMETICS; CYCLIC HOMOOLIGOMERS; AMINO-ACIDS;

D O I：

10.1016/j.carres.2009.03.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A short and highly efficient route to the alpha-anomer of a furanoid sugar-aza-crown ether was developed by a one-pot reductive amination of an alpha-anomer C-ribosyl azido aldehyde. In addition, the beta-anomer furanoid sugar-aza-crown ether was synthesized from a linear disaccharide precursor via amidation and then followed by microwave-assisted amide reduction. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1020 / 1023

页数：4

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