Counterion Effects in a Gold-Catalyzed Synthesis of Pyrroles from Alkynyl Aziridines

被引：152

作者：

Davies, Paul W. ^{[1
]}

Martin, Nicolas ^{[1
]}

机构：

[1] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 11期

基金：

英国工程与自然科学研究理事会;

关键词：

AMINATION/ANNULATION REACTIONS; CYCLOISOMERIZATION; CYCLIZATION; PLATINUM; KETONES; 1,2-MIGRATION; DERIVATIVES; MIGRATION; ALLENES;

D O I：

10.1021/ol900609f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aryl-substituted N-tosyl alkynyl aziridines undergo a gold-catalyzed ring expansion to afford 2,5-substituted pyrrole products. Under certain conditions, a ring-expansion and rearrangement leads to 2,4-substituted pyrroles. The reaction pathway is determined by the counterion to the gold catalyst.

引用

页码：2293 / 2296

页数：4

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