Can magneto-plasmonic nanohybrids efficiently combine photothermia with magnetic hyperthermia?

被引:107
作者
Espinosa, Ana [1 ,2 ]
Bugnet, Mathieu [3 ,4 ]
Radtke, Guillaume [5 ]
Neveu, Sophie [6 ]
Botton, Gianluigi A. [3 ,4 ]
Wilhelm, Claire [1 ,2 ]
Abou-Hassan, Ali [6 ]
机构
[1] CNRS, Lab Mat & Syst Complexes MSC, UMR 7057, F-75205 Paris 13, France
[2] Univ Paris Diderot, F-75205 Paris 13, France
[3] McMaster Univ, Dept Mat Sci & Engn, Hamilton, ON L8S 4M1, Canada
[4] McMaster Univ, Canadian Ctr Elect Microscopy, Hamilton, ON L8S 4M1, Canada
[5] UPMC, CNRS, IMPMC, UMR 7590, F-75005 Paris, France
[6] Univ Paris 06, Sorbonne Univ, CNRS, PHENIX,UMR 8234, F-75252 Paris, France
基金
加拿大创新基金会; 加拿大自然科学与工程研究理事会;
关键词
GOLD NANOPARTICLES; CORE NANOPARTICLES; SIZE; NANOSHELLS; THERAPY; ABSORPTION; NANOCUBES; ABLATION; DESIGN;
D O I
10.1039/c5nr06168g
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Multifunctional hybrid-design nanomaterials appear to be a promising route to meet the current therapeutics needs required for efficient cancer treatment. Herein, two efficient heat nano-generators were combined into a multifunctional single nanohybrid (a multi-core iron oxide nanoparticle optimized for magnetic hyperthermia, and a gold branched shell with tunable plasmonic properties in the NIR region, for photothermal therapy) which impressively enhanced heat generation, in suspension or in vivo in tumours, opening up exciting new therapeutic perspectives.
引用
收藏
页码:18872 / 18877
页数:6
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