Biological applications of magnetic nanoparticles

被引：1040

作者：

Colombo, Miriam ^{[1
]}

Carregal-Romero, Susana ^{[2
,3
]}

Casula, Maria F. ^{[4
,5
]}

Gutierrez, Lucia ^{[6
,7
]}

Morales, Maria P. ^{[6
]}

Boehm, Ingrid B. ^{[8
]}

Heverhagen, Johannes T. ^{[8
]}

Prosperi, Davide ^{[1
]}

Parak, Wolfgang. J. ^{[2
,3
]}

机构：

[1] Univ Milano Bicocca, Dipartimento Biotecnol & Biosci, Milan, Italy

[2] Univ Marburg, Dept Phys, D-3550 Marburg, Germany

[3] Univ Marburg, WZMW, D-3550 Marburg, Germany

[4] Univ Cagliari, Dipartimento Sci Chim, Cagliari, Italy

[5] Univ Cagliari, INSTM, Cagliari, Italy

[6] CSIC, ICMM, Dept Biomat & Mat Bioinspirados, Madrid, Spain

[7] Univ Western Australia, Sch Phys M013, Crawley, Australia

[8] Univ Marburg, Dept Diagnost Radiol, Marburg, Germany

来源：

CHEMICAL SOCIETY REVIEWS | 2012年 / 41卷 / 11期

关键词：

IRON-OXIDE NANOPARTICLES; NEURAL STEM-CELLS; DRUG-DELIVERY-SYSTEM; MRI CONTRAST AGENTS; IN-VIVO TRACKING; TARGETING GENE DELIVERY; SPINAL-CORD-INJURY; DENDRITIC CELLS; CANCER-THERAPY; INTRACELLULAR HYPERTHERMIA;

D O I：

10.1039/c2cs15337h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this review an overview about biological applications of magnetic colloidal nanoparticles will be given, which comprises their synthesis, characterization, and in vitro and in vivo applications. The potential future role of magnetic nanoparticles compared to other functional nanoparticles will be discussed by highlighting the possibility of integration with other nanostructures and with existing biotechnology as well as by pointing out the specific properties of magnetic colloids. Current limitations in the fabrication process and issues related with the outcome of the particles in the body will be also pointed out in order to address the remaining challenges for an extended application of magnetic nanoparticles in medicine.

引用

收藏

页码：4306 / 4334

页数：29

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