Electrochemical sensors based on conducting polymer- polypyrrole

被引：718

作者：

Ramanavicius, A.

Ramanaviciene, A.

Malinauskas, A.

机构：

[1] Vilnius State Univ, Dept Analyt & Environm Chem, LT-03225 Vilnius, Lithuania

[2] Vilnius State Univ, Inst Immunol, Lab Immunoanal & Nanotechnol, LT-08409 Vilnius, Lithuania

[3] Inst Chem, Dept Organ Chem, LT-01108 Vilnius, Lithuania

来源：

ELECTROCHIMICA ACTA | 2006年 / 51卷 / 27期

关键词：

conducting polymers; polypyrrole; biosensor; DNA sensor; immunosensor; molecularly imprinted polymers; bioelectrochemistry; nanotechnology; nanobiotechnology;

D O I：

10.1016/j.electacta.2005.11.052

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Conducting polymers can be exploited as an excellent tool for the preparation of nanocomposites with nano-scaled biomolecules. Polypyrrole (Ppy) is one of the most extensively used conducting polymers in design of bioanalytical sensors. In this review article significant attention is paid to immobilization of biologically active molecules within Ppy during electrochemical deposition of this polymer. Such unique properties of this polymer as prevention of some undesirable electrochemical interactions and facilitation of electron transfer from some redox enzymes are discussed. Recent advances in application of polypyrrole in immunosensors and DNA sensors are presented. Some new electrochemical target DNA and target protein detection methods based on changes of semiconducting properties of electrochemically generated Ppy doped by affinity agents are introduced. Recent progress and problems in development of molecularly imprinted polypyrrole are considered. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：6025 / 6037

页数：13

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[61] DNA as a 'nanomaterial' [J].