Human prefrontal cortex: Processing and representational perspectives

被引:467
作者
Wood, JN [1 ]
Grafman, J [1 ]
机构
[1] NINDS, Cognit Neurosci Sect, NIH, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrn1033
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Through evolution, humans have acquired 'higher' cognitive skills-such as language, reasoning and planning-and complex social behaviour. Evidence from neuropsychological and neuroimaging research indicates that the prefrontal cortex (PFC) underlies much of this higher cognition. A number of theories have been proposed for how the PFC might achieve this. Although many of these theories focus on the types of 'process' that the PFC carries out, we argue for the validity of a representational approach to understanding PFC function.
引用
收藏
页码:139 / 147
页数:9
相关论文
共 109 条
  • [91] Decision-making in mania: a PET study
    Rubinsztein, JS
    Fletcher, PC
    Rogers, RD
    Ho, LW
    Aigbirhio, FI
    Paykel, ES
    Robbins, TW
    Sahakian, BJ
    [J]. BRAIN, 2001, 124 : 2550 - 2563
  • [92] Sustained attention deficits in patients with right frontal lesions
    Rueckert, L
    Grafman, J
    [J]. NEUROPSYCHOLOGIA, 1996, 34 (10) : 953 - 963
  • [93] Retrieval processing and episodic memory
    Rugg, MD
    Wilding, EL
    [J]. TRENDS IN COGNITIVE SCIENCES, 2000, 4 (03) : 108 - 115
  • [94] Humans and great apes share a large frontal cortex
    Semendeferi, K
    Lu, A
    Schenker, N
    Damasio, H
    [J]. NATURE NEUROSCIENCE, 2002, 5 (03) : 272 - 276
  • [95] Semendeferi K, 2001, AM J PHYS ANTHROPOL, V114, P224, DOI 10.1002/1096-8644(200103)114:3<224::AID-AJPA1022>3.3.CO
  • [96] 2-9
  • [97] Encoding of sequence and boundaries of scripts following prefrontal lesions
    Sirigu, A
    Zalla, T
    Pillon, B
    Grafman, J
    Agid, Y
    Dubois, B
    [J]. CORTEX, 1996, 32 (02) : 297 - 310
  • [98] Frontal lobe contributions to theory of mind
    Stone, VE
    Baron-Cohen, S
    Knight, RT
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 1998, 10 (05) : 640 - 656
  • [99] Anterior prefrontal cortex mediates rule learning in humans
    Strange, BA
    Henson, RNA
    Friston, KJ
    Dolan, RJ
    [J]. CEREBRAL CORTEX, 2001, 11 (11) : 1040 - 1046
  • [100] Dissociation of attentional processes in patients with focal frontal and posterior lesions
    Stuss, DT
    Toth, JP
    Franchi, D
    Alexander, MP
    Tipperd, S
    Craik, FIM
    [J]. NEUROPSYCHOLOGIA, 1999, 37 (09) : 1005 - 1027