Review coupling of capillary electrochromatography to mass spectrometry

被引：80

作者：

Klampfl, CW ^{[1
]}

机构：

[1] Johannes Kepler Univ Linz, Inst Analyt Chem, A-4040 Linz, Austria

来源：

JOURNAL OF CHROMATOGRAPHY A | 2004年 / 1044卷 / 1-2期

关键词：

reviews; electrochromatography; mass spectrometry; interfaces; CEC-MS;

D O I：

10.1016/j.chroma.2004.04.072

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review discusses the development of capillary electrochromatography (CEC) coupled to mass spectrometric (MS) detection over the last few years. Major topics addressed are instrumental setups employed and applications of this technology published in the recent literature. The instrumental section includes a discussion of the most commonly used interfaces for the hyphenation of CEC and MS as well as ionization techniques. Applications reviewed in this paper come from a variety of different fields such as the analysis of biomolecules like proteins, peptides, amino acids or carbohydrates, chiral separations or the analysis of pharmaceutical an their metabolites in a series of matrices. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：131 / 144

页数：14

共 115 条

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