Trisubstituted aziridine ring-opening by phenol derivatives:: Stereo- and regioselective formation of chiral tertiary alkyl-aryl ethers

被引：40

作者：

Li, Pixu ^{[1
]}

Forbeck, Erin M. ^{[1
]}

Evans, Cory D. ^{[1
]}

Joullie, Madeleine M. ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 22期

关键词：

D O I：

10.1021/ol062010w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An unprecedented stereo- and regioselective trisubstituted aziridine ring-opening by phenol derivatives was discovered. The reaction features very mild reaction conditions and broad functional group compatibility, which provides a good method for the stereoselective formation of tertiary alkyl-aryl ethers in highly functionalized systems.

引用

收藏

页码：5105 / 5107

页数：3

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