Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

被引：76

作者：

Hendrickson, CL ^{[1
]}

Emmett, MR ^{[1
]}

机构：

[1] Florida State Univ, Natl High Magnet Field Lab, Ctr Interdisciplinary Magnet Resonance, Tallahassee, FL 32310 USA

来源：

ANNUAL REVIEW OF PHYSICAL CHEMISTRY | 1999年 / 50卷

关键词：

ESI; FT MS; FT-ICR; ICR;

D O I：

10.1146/annurev.physchem.50.1.517

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The basic principles and recent advances in electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry are reviewed. A brief history of electrospray ionization is provided, along with a complete technical description of the technique, electrospray ionization variations, and advantages. Next, the fundamental principles of Fourier transform ion cyclotron resonance mass spectrometry are covered, including ion cyclotron motion, ion cyclotron resonance excitation, and image current detection. Instrumentation and methods used to couple these techniques are then described. Topics include ion source configuration, ion transport through a strong magnetic field gradient, and ion trapping methods. The article concludes with selected applications that highlight the strengths of electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

引用

页码：517 / 536

页数：20

共 100 条

[41] HIGH-PERFORMANCE DETECTION OF BIOMOLECULES USING A HIGH MAGNETIC-FIELD ELECTROSPRAY-IONIZATION SOURCE FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE MASS-SPECTROMETER [J].