The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis

被引：224

作者：

Emerich, Dwaine F. ^{[1
]}

Thanos, Christopher G. ^{[1
]}

机构：

[1] LCT BioPharma Inc, Providence, RI USA

来源：

BIOMOLECULAR ENGINEERING | 2006年 / 23卷 / 04期

关键词：

nanoparticle; molecular diagnosis; drug delivery; targeted delivery; nanomedicine;

D O I：

10.1016/j.bioeng.2006.05.026

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Nanotechnology, or systems/device manufacture at the molecular level, is a multidisciplinary scientific field undergoing explosive development. The genesis of nanotechnology can be traced to the promise of revolutionary advances across medicine, communications, genomics and robotics. Without doubt one of the greatest values of nanotechnology will be in the development of new and effective medical treatments (i.e., nanomedicine). This review focuses on the potential of nanomedicine as it specifically relates to (1) the development of nanoparticles for enabling and improving the targeted delivery of therapeutic agents; (2) developing novel and more effective diagnostic and screening techniques to extend the limits of molecular diagnostics providing point-of-care diagnosis and more personalized medicine. (c) 2006 Elsevier B.V. All rights reserved.

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收藏

页码：171 / 184

页数：14

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