Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits in immature and mature cultured rat calvarial osteoblasts

被引:40
作者
Hinoi, E [1 ]
Fujimori, S [1 ]
Takemori, A [1 ]
Kurabayashi, H [1 ]
Nakamura, Y [1 ]
Yoneda, Y [1 ]
机构
[1] Kanazawa Univ, Fac Pharmaceut Sci, Dept Mol Pharmacol, Kanazawa, Ishikawa 9200934, Japan
关键词
glutamate; AMPA receptors; GluR3; KA1; KA2; osteoblast; RT-PCR;
D O I
10.1016/S0006-8993(02)02726-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Reverse transcription polymerase chain reaction revealed expression of mRNA for particular subunits of ionotropic glutamate receptors (iGluR) in primary cultures of rat calvarial osteoblastic cells under immature to mature states. These included GluR3, KA1 and KA2 subunits, in addition to NR1 and NR2D subunits. These results suggest that glutamate may play an unidentified role in mechanisms associated with cellular development through particular subunits of iGluR in rat calvarial osteoblasts. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:112 / 116
页数:5
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