Reverse transcription polymerase chain reaction revealed expression of mRNA for particular subunits of ionotropic glutamate receptors (iGluR) in primary cultures of rat calvarial osteoblastic cells under immature to mature states. These included GluR3, KA1 and KA2 subunits, in addition to NR1 and NR2D subunits. These results suggest that glutamate may play an unidentified role in mechanisms associated with cellular development through particular subunits of iGluR in rat calvarial osteoblasts. (C) 2002 Elsevier Science B.V. All rights reserved.
机构:
Washington Univ, Sch Med, Dept Pathol, Barnes Jewish Hosp N, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol, Barnes Jewish Hosp N, St Louis, MO 63110 USA
机构:
Washington Univ, Sch Med, Dept Pathol, Barnes Jewish Hosp N, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol, Barnes Jewish Hosp N, St Louis, MO 63110 USA