Reactive oxygen species signaling in vascular smooth muscle cells

被引：282

作者：

Clempus, Roza E. ^{[1
]}

Griendling, Kathy K. ^{[1
]}

机构：

[1] Emory Univ, Dept Med, Div Cardiol, Atlanta, GA 30322 USA

来源：

CARDIOVASCULAR RESEARCH | 2006年 / 71卷 / 02期

关键词：

oxygen radicals; NADPH oxidase; signal transduction; smooth muscle;

D O I：

10.1016/j.cardiores.2006.02.033

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Reactive oxygen species (ROS) have been shown to function as important signaling molecules in the cardiovascular system. Vascular smooth muscle cells (VSMCs) contain several sources of ROS, among which the NADPH oxidases are predominant. In VSMCs, ROS mediate many pathophysiological processes, such as growth, migration, apoptosis and secretion of inflammatory cytokines, as well as physiological processes, such as differentiation, by direct and indirect effects at multiple signaling levels. Therefore, it becomes critical to understand the different roles ROS play in the physiology and pathophysiology of VSMCs. (c) 2006 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

引用

页码：216 / 225

页数：10

共 104 条

[91] RETRACTED: CAbl tyrosine kinase mediates reactive oxygen species and caveolin-dependent AT1 receptor signaling in vascular smooth muscle -: Role in vascular hypertrophy (Retracted article. See vol. 106, pg. 1784, 2010) [J].

Ushio-Fukai, M ;

Zuo, L ;

Ikeda, S ;

Tojo, T ;

Patrushev, NA ;

Alexander, RW .

CIRCULATION RESEARCH, 2005, 97 (08) :829-836

[92] RETRACTED: Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells (Retracted Article) [J].

Ushio-Fukai, M ;

Griendling, KK ;

Becker, PL ;

Hilenski, L ;

Halleran, S ;

Alexander, RW .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (04) :489-495

[93] Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells [J].

Ushio-Fukai, M ;

Alexander, RW ;

Akers, M ;

Yin, QQ ;

Fujio, Y ;

Walsh, K ;

Griendling, KK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (32) :22699-22704

[94] p38 mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II - Role in vascular smooth muscle cell hypertrophy [J].

Ushio-Fukai, M ;

Alexander, RW ;

Akers, M ;

Griendling, KK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (24) :15022-15029

[95] Role of p22phox in angiotensin II and platelet-derived growth factor AA induced activator protein I activation in vascular smooth muscle cells [J].

Viedt, C ;

Fei, JW ;

Krieger-Brauer, HI ;

Brandes, RP ;

Teupser, D ;

Kamimura, M ;

Katus, HA ;

Kreuzer, J .

JOURNAL OF MOLECULAR MEDICINE-JMM, 2004, 82 (01) :31-38

[96] Differential activation of mitogen-activated protein kinases in smooth mascle cells by angiotensin II -: Involvement of p22phox and reactive oxygen species [J].

Viedt, C ;

Soto, U ;

Krieger-Brauer, HI ;

Fei, JW ;

Elsing, C ;

Kübler, W ;

Kreuzer, J .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2000, 20 (04) :940-948

[97] Reactive oxygen species-sensitive p38 MAPK controls thrombin-induced migration of vascular smooth muscle cells [J].

Wang, ZB ;

Castresana, MR ;

Newman, WH .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2004, 36 (01) :49-56

[98] Reactive oxygen and NF-κB in VEGF-induced migration of human vascular smooth muscle cells [J].

Wang, ZB ;

Castresana, MR ;

Newman, WH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 285 (03) :669-674

[99] Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration [J].

Weber, DS ;

Taniyama, Y ;

Rocic, P ;

Seshiah, PN ;

Dechert, MA ;

Gerthoffer, WT ;

Griendling, KK .

CIRCULATION RESEARCH, 2004, 94 (09) :1219-1226

[100] Lysophosphatidylcholine activates extracellular signal-regulated kinases 1/2 through reactive oxygen species in rat vascular smooth muscle cells [J].

Yamakawa, T ;

Tanaka, S ;

Yamakawa, Y ;

Kamei, J ;

Numaguchi, K ;

Motley, ED ;

Inagami, T ;

Eguchi, S .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (05) :752-758

← 2 3 4 5 6 7 8 9 10 11 →