The HeArt of regeneration

被引：12

作者：

Curado, Silvia

Stainier, Didier Y. R.

机构：

[1] Univ Calif San Francisco, Dept Biochem & Biophys, Program Dev Biol, San Francisco, CA 94158 USA

[2] Univ Calif San Francisco, Dept Biochem & Biophys, Program Genet & Human Genet, San Francisco, CA 94158 USA

[3] Univ Calif San Francisco, Dept Biochem & Biophys, Inst Cardiovasc Res, San Francisco, CA 94158 USA

来源：

CELL | 2006年 / 127卷 / 03期

关键词：

D O I：

10.1016/j.cell.2006.10.025

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Fish and amphibian hearts are known to regenerate after partial resection, but the molecular mechanisms underlying this process remain unclear. In this issue of Cell, Lepilina et al. (2006) analyze regeneration in the zebrafish heart. Their work indicates that new cardiomyocytes originate from undifferentiated progenitor cells and reveals a critical role for the epicardium, the cellular layer that covers the heart.

引用

收藏

页码：462 / 464

页数：3

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