17O-decoupled 1H spectroscopy and imaging with a surface coil:: STEAM decoupling

被引：10

作者：

Charagundla, SR ^{[1
]}

Duvvuri, U ^{[1
]}

Noyszewski, EA ^{[1
]}

Dandora, R ^{[1
]}

Stolpen, AH ^{[1
]}

Leigh, JS ^{[1
]}

Reddy, R ^{[1
]}

机构：

[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA

来源：

JOURNAL OF MAGNETIC RESONANCE | 2000年 / 143卷 / 01期

关键词：

O-17; decoupling; stimulated echo; surface coil;

D O I：

10.1006/jmre.1999.1948

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

O-17-decoupled H-1 spin-echo imaging has been reported as a means of indirect O-17 detection, with potential application to measurement of blood how and metabolism. In its current form, O-17 decoupling requires large RF amplitudes and a 180 degrees refocusing pulse, complicating its application in volume and surface coils, respectively. To overcome this problem, we have developed an O-17-decoupled proton stimulated echo sequence ("STEAM decoupling") to allow O-17 detection with a surface coil. A high B-1 amplitude is easily generated, allowing complete decoupling of O-17 and H-1. Slice-selective, O-17-decoupled H-1 imaging is readily performed and the sequence is easily adapted for localized spectroscopy. Intrinsic correction for variations in B-1 and further compensation for B-1 inhomogeneity are discussed. (C) 2000 Academic Press.

引用

页码：39 / 44

页数：6