Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker

被引：317

作者：

Hylton, Nola ^{[1
]}

机构：

[1] Univ Calif San Francisco, San Francisco, CA 94143 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2006年 / 24卷 / 20期

关键词：

D O I：

10.1200/JCO.2006.06.8080

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is being used in oncology as a noninvasive method for measuring properties of the tumor microvasculature. There is potential for DCE-MRI to be used as an imaging biomarker to measure antiangiogenic effects of cancer treatments. This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials.

引用

页码：3293 / 3298

页数：6

共 36 条

[1] Patterns of peripheral enhancement in breast masses: Correlation of findings on contrast medium enhanced MRI with histologic features and tumor angiogenesis
Buadu, LD
Murakami, J
Murayama, S
Hashiguchi, N
Sakai, S
Toyoshima, S
Masuda, T
Kuroki, S
Ohno, S
[J]. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1997, 21 (03) : 421 - 430
[2] Breast lesions: Correlation of contrast medium enhancement patterns on MR images with histopathologic findings and tumor angiogenesis
Buadu, LD
Murakami, J
Murayama, S
Hashiguchi, N
Sakai, S
Masuda, K
Toyoshima, S
Kuroki, S
Ohno, S
[J]. RADIOLOGY, 1996, 200 (03) : 639 - 649
[3] Microvessel density in invasive breast cancer assessed by dynamic Gd-DTPA enhanced MRI
Buckley, DL
Drew, PJ
Mussurakis, S
Monson, JRT
Horsman, A
[J]. JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, 1997, 7 (03): : 461 - 464
[4] Esserman Laura, 1999, Breast J, V5, P13, DOI 10.1046/j.1524-4741.1999.005001013.x
[5] Evelhoch JL, 1999, JMRI-J MAGN RESON IM, V10, P254, DOI 10.1002/(SICI)1522-2586(199909)10:3<254::AID-JMRI5>3.0.CO
[6] 2-9
[7] Small peripheral pulmonary carcinomas evaluated with dynamic MR imaging:: Correlation with tumor vascularity and prognosis
Fujimoto, K
Abe, T
Müller, NL
Terasalki, H
Kato, S
Sadohara, J
Kono, R
Edamitsu, O
Ishitake, T
Hayashi, A
Rikimaru, T
Hayabuchi, N
[J]. RADIOLOGY, 2003, 227 (03) : 786 - 793
[8] Magnetic resonance imaging reveals functional diversity of the vasculature in benign and malignant breast lesions
Furman-Haran, E
Schechtman, E
Kelcz, F
Kirshenbaum, K
Degani, H
[J]. CANCER, 2005, 104 (04) : 708 - 718
[9] Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a useful modality for the precise detection and staging of early prostate cancer
Hara, N
Okuizumi, M
Koike, H
Kawaguchi, M
Bilim, V
[J]. PROSTATE, 2005, 62 (02) : 140 - 147
[10] Hawighorst H, 1997, CANCER RES, V57, P4777

← 1 2 3 4 →