Highly Water-Dispersible Biocompatible Magnetite Particles with Low Cytotoxicity Stabilized by Citrate Groups

被引：935

作者：

Liu, Jia ^{[1
,2
]}

Sun, Zhenkun ^{[1
,2
]}

Deng, Yonghui ^{[1
,2
]}

Zou, Ying ^{[1
,2
]}

Li, Chunyuan ^{[1
,2
]}

Guo, Xiaohui ^{[1
,2
]}

Xiong, Liqin ^{[1
,2
]}

Gao, Yuan ^{[1
,2
]}

Li, Fuyou ^{[1
,2
]}

Zhao, Dongyuan ^{[1
,2
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai Key Lab Mol Catalysis & Innovat Mat, Shanghai 200433, Peoples R China

[2] Fudan Univ, Dept Chem, Adv Mat Lab, Shanghai 200433, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 32期

关键词：

biocompatibility; colloids; magnetite; nanocrystals; superparamagnetism; LIGAND-EXCHANGE; NANOPARTICLES; MONODISPERSE; SIZE; CANCER; SHAPE; NANOCRYSTALS; FUNCTIONALIZATION; DOPAMINE; AGENT;

D O I：

10.1002/anie.200901566

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Uniform magnetite particles stabilized by citrate groups were successfully synthesized by a modified hightemperature solvothermal reaction. Cell imaging reveals that the water-dispersible particles can readily penetrate into cells without destroying them, indicating an excellent biocompatibility. A high enrichment capacity of the magnetite particles for separation of trace peptides is observed. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：5875 / 5879

页数：5

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