Initiated CVD of Poly(2-Hydroxyethyl Methacrylate) Hydrogels: Synthesis, Characterization and In-vitro Biocompatibility

被引：35

作者：

Bose, Ranjita K. ^{[1
]}

Lau, Kenneth K. S. ^{[1
]}

机构：

[1] Drexel Univ, Dept Chem & Biol Engn, Philadelphia, PA 19104 USA

来源：

CHEMICAL VAPOR DEPOSITION | 2009年 / 15卷 / 4-6期

关键词：

cell adhesion; cytotoxicity; hydrogel; initiated CVD; PHEMA; CHEMICAL-VAPOR-DEPOSITION; 2-HYDROXYETHYL METHACRYLATE; CELL ADHESION; PLASMA; FILMS; ADSORPTION; ICVD; CYTOTOXICITY; ACRYLATES); ROUGHNESS;

D O I：

10.1002/cvde.200806748

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.

引用

页码：150 / 155

页数：6

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