Wide-field optical imaging of surface nanostructures

被引:47
作者
Ausserre, Dominique [1 ]
Valignat, Marie-Pierre
机构
[1] Univ Maine, CNRS, UMR 6087, F-72085 Le Mans 9, France
[2] Aix Marseille Univ, UMR 6212, CNRS, INSERM,UMR 600, F-13288 Marseille, France
关键词
D O I
10.1021/nl060353h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We present a new technique that increases the sensitivity of incoherent light optical microscopy to a point where it becomes possible to directly visualize ultrathin films (similar to nanometers) and isolated nano-objects. The technique is based on the use of nonreflecting substrate surfaces for cross-polarized reflected light microscopy. These surfaces generate a contrast enhancement of about 2 orders of magnitude, extending the application field of wide-field optical microscopy toward the nanoworld. The efficiency of the method is proven experimentally on well-characterized samples. Wide-field imaging of a nonlabeled lambda-DNA molecule is also presented.
引用
收藏
页码:1384 / 1388
页数:5
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