A 94-μW 10-b Neural Recording Front-End for an Implantable Brain-Machine-Brain Interface Device

被引:5
作者
Azin, Meysam [1 ]
Mohseni, Pedram [1 ]
机构
[1] Case Western Reserve Univ, Dept Elect Engn & Comp Sci, Cleveland, OH 44106 USA
来源
2008 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE - INTELLIGENT BIOMEDICAL SYSTEMS (BIOCAS) | 2008年
关键词
Brain-machine-brain interface; Neural recording; Neuroanatomical rewiring; Neurostimulation;
D O I
10.1109/BIOCAS.2008.4696914
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
This paper describes a fully integrated neural recording front-end comprising a low-noise two-stage amplification circuitry and a 10-b successive approximation register (SAR)-based ADC as part of a fully implantable brain-machine-brain interface (BMBI) device for neuroanatomical rewiring of cortical circuitry in an injured brain. Fabricated using the TSMC 0.35 mu m 2P/4M n-well CMOS process, the accoupled amplification circuitry provides a maximum mid-band ac gain of similar to 52 dB and features a measured input-referred voltage noise of 3.5 mu V(rms) from 0.1 Hz to 12.8 kHz, while dissipating similar to 78 mu W from 2 V. The SAR ADC features an ENOB of similar to 9.4 for maximum sampling frequency of similar to 45 kSa/s, while dissipating only 16 mu W. Benchtop as well as in vitro measurement results in saline are reported.
引用
收藏
页码:221 / 224
页数:4
相关论文
共 7 条
[1]   A high-output-impedance current microstimulator for anatomical rewiring of cortical circuitry [J].
Azin, Meysam ;
Mohseni, Pedram .
PROCEEDINGS OF 2008 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS, VOLS 1-10, 2008, :2502-2505
[2]   Extensive cortical rewiring after brain injury [J].
Dancause, N ;
Barbay, S ;
Frost, SB ;
Plautz, EJ ;
Chen, DF ;
Zoubina, EV ;
Stowe, AM ;
Nudo, RJ .
JOURNAL OF NEUROSCIENCE, 2005, 25 (44) :10167-10179
[3]   A low-power low-noise CMOS amplifier for neural recording applications [J].
Harrison, RR ;
Charles, C .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2003, 38 (06) :958-965
[4]   Long-term motor cortex plasticity induced by an electronic neural implant [J].
Jackson, Andrew ;
Mavoori, Jaideep ;
Fetz, Eberhard E. .
NATURE, 2006, 444 (7115) :56-60
[5]   SOLID-STATE MICROSENSORS FOR CORTICAL NERVE RECORDINGS [J].
NAJAFI, K .
IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 1994, 13 (03) :375-387
[6]   Mechanisms for recovery of motor function following cortical damage [J].
Nudo, Randolph J. .
CURRENT OPINION IN NEUROBIOLOGY, 2006, 16 (06) :638-644
[7]  
Tsividis Y., 1999, OPERATION MODELING M, V2nd