Palladium-Catalyzed Direct C-3 Arylations of Indoles with an Air-Stable HASPO

被引：79

作者：

Ackermann, Lutz ^{[1
]}

Barfuesser, Sebastian ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

SYNLETT | 2009年 / 05期

关键词：

C-H bond functionalization; heteroarenes; indoles; regioselectivity; palladium; H BOND ACTIVATION; CROSS-COUPLING REACTIONS; C-H; FREE (NH)-INDOLES; PHOSPHINE OXIDES; ROOM-TEMPERATURE; ARYL; FUNCTIONALIZATION; PRELIGANDS; CHLORIDES;

D O I：

10.1055/s-0028-1087951

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient direct arylations of indoles occurred highly regioselectively at position C-3 with an in situ generated palladium complex derived from an air-stable HASPO, which enabled syntheses of diversely functionalized indoles, also with sterically hindered substrates.

引用

页码：808 / 812

页数：5

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