Hydroamination/Heck reaction sequence for a highly regioselective one-pot synthesis of indoles using 2-chloroaniline

被引：90

作者：

Ackermann, L ^{[1
]}

Kaspar, LT ^{[1
]}

Gschrei, CJ ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 24期

关键词：

D O I：

10.1039/b411571f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A one-pot indole synthesis consisting of a highly regioselective TiCl4-catalyzed hydroamination and a 5-endo Heck cyclization starting from 2-chloroaniline is described, using an in-situ generated, sterically hindered imidazol-2-ylidene palladium complex.

引用

页码：2824 / 2825

页数：2

共 28 条

[1] TiCl4-catalyzed intermolecular hydroamination reactions of norbornene [J].