Understanding Memory Dysfunction

被引:45
作者
Budson, Andrew E. [1 ,2 ]
机构
[1] Bedford VA Hosp, Geriatr Res Educ Clin Ctr, Ctr Translat Cognit Neurosci, Bedford, MA 01730 USA
[2] Boston Univ, Sch Med, Dept Neurol, Rush Alzheimers Dis Ctr, Boston, MA 02118 USA
关键词
memory; Alzheimer disease; frontal lobes; false memory; memory distortions; ALZHEIMERS-DISEASE; WORKING-MEMORY; PARKINSONS-DISEASE; PREFRONTAL CORTEX; BRAIN ACTIVITY; TEMPORAL-LOBE; FRONTAL-CORTEX; MOTOR SEQUENCE; LEWY BODIES; DEMENTIA;
D O I
10.1097/NRL.0b013e318188040d
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Although traditionally memory has been viewed as it simple concept, converging, and complementary evidence from patient Studies and more recent neuroimaging research suggest that memory is a collection of mental abilities that use different neuroanatomical systems within the brain. Neurologic injury may cause damage to one or more of these memory systems. Review Summary: In this review it number of different memory systems are discussed. including their function, neuroanatomy. and the different disorders that disrupt them. Episodic memory, the most clinically relevant memory system. depends upon the hippocampus and other medial temporal lobe structures. the limbic system, and the frontal lobes. Several other kinds of memory are contrasted with episodic memory, including semantic memory, simple classic conditioning. procedural memory, priming. and working memory. Conclusion: Improved understanding of these different types of memory will aid the clinician in the diagnosis and treatment of the memory, disorders of their patients. As more specific therapeutic strategies are developed for the treatment of diseases which cause memory dysfunction, this knowledge will become increasingly important.
引用
收藏
页码:71 / 79
页数:9
相关论文
共 69 条
[11]   Suppression of false recognition in Alzheimer's disease and in patients with frontal lobe lesions [J].
Budson, AE ;
Sullivan, AL ;
Mayer, E ;
Daffner, KR ;
Black, PM ;
Schacter, DL .
BRAIN, 2002, 125 :2750-2765
[12]   Perception, attention, and working memory are disproportionately impaired in dementia with Lewy bodies compared with Alzheimer's disease [J].
Calderon, J ;
Perry, RJ ;
Erzinclioglu, SW ;
Berrios, GE ;
Dening, TR ;
Hodges, JR .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2001, 70 (02) :157-164
[13]   The autonomic-related cortex: Pathology in Alzheimer's disease [J].
Chu, CC ;
Tranel, D ;
Damasio, AR ;
VanHoesen, GW .
CEREBRAL CORTEX, 1997, 7 (01) :86-95
[15]   A neural basis for lexical retrieval [J].
Damasio, H ;
Grabowski, TJ ;
Tranel, D ;
Hichwa, RD ;
Damasio, AR .
NATURE, 1996, 380 (6574) :499-505
[16]   Similar network activated by young and old adults during the acquisition of a motor sequence [J].
Daselaar, SM ;
Rombouts, SARB ;
Veltman, DJ ;
Raaijmakers, JGW ;
Jonker, C .
NEUROBIOLOGY OF AGING, 2003, 24 (07) :1013-1019
[17]   Eyeblink-related areas in human cerebellum as shown by fMRI [J].
Dimitrova, A ;
Weber, J ;
Maschke, M ;
Elles, HG ;
Kolb, FP ;
Forsting, M ;
Diener, HC ;
Timmann, D .
HUMAN BRAIN MAPPING, 2002, 17 (02) :100-115
[18]   Sensitivity and specificity of memory dysfunction in schizophrenia: A comparison with major depression [J].
Egeland, J ;
Sundet, K ;
Rund, BR ;
Asbjornsen, A ;
Hugdahl, K ;
Landro, NI ;
Lund, A ;
Roness, A ;
Stordal, KI .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 2003, 25 (01) :79-93
[19]   Treatment of attention-deficit-hyperactivity disorder [J].
Elia, J ;
Ambrosini, PJ ;
Rapoport, JL .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (10) :780-788
[20]   Rivastigmine for dementia associated with Parkinson's disease [J].
Emre, M ;
Aarsland, D ;
Albanese, A ;
Byrne, EJ ;
Deuschl, G ;
De Deyn, PP ;
Durif, F ;
Kulisevsky, J ;
van Laar, T ;
Lees, A ;
Poewe, W ;
Robillard, A ;
Rosa, MM ;
Wolters, E ;
Quarg, P ;
Tekin, S ;
Lane, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (24) :2509-2518