Flexible miniature compound lens design for high-resolution optical coherence tomography balloon imaging catheter

被引:48
作者
Fu, Henry L. [1 ]
Leng, Yuxin [1 ]
Cobb, Michael J. [1 ]
Hsu, Kevin [2 ]
Hwang, Joo Ha [3 ]
Li, Xingde [1 ]
机构
[1] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA
[2] Micron Opt, Atlanta, GA 30345 USA
[3] Univ Washington, Dept Med, Div Gastroenterol, Seattle, WA 98195 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
optical coherence tomography; endomicroscopy; balloon catheter; internal organ imaging;
D O I
10.1117/1.3037340
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We report on a new optics design for an optical coherence tomography (OCT) balloon imaging catheter. The design involves a miniature compound gradient-index (GRIN) rod lens, which consists of a fiber optic mode-field reducer and relay rod lenses to achieve predictable high lateral resolution at a desired large working distance. The compound lens design significantly simplifies the engineering process for an OCT catheter and enables 3-D full circumferential cross sectional imaging of large luminal organs such as human esophagus. An as-designed OCT catheter is developed and demonstrated for real-time in vivo swine esophagus imaging in a 3-D spiral fashion. (C) 2008 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3037340]
引用
收藏
页数:3
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