Oxygen saturation-dependent absorption and scattering of blood

被引:213
作者
Faber, DJ [1 ]
Aalders, MCG
Mik, EG
Hooper, BA
van Gemert, MJC
van Leeuwen, TG
机构
[1] Univ Amsterdam, Acad Med Ctr, Ctr Laser, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Physiol, NL-1105 AZ Amsterdam, Netherlands
[3] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[4] Duke Univ, Ctr Emerging Cardiovasc Technol, Durham, NC 27708 USA
[5] Univ Twente, Biomed Technol Inst, NL-7500 AE Enschede, Netherlands
关键词
D O I
10.1103/PhysRevLett.93.028102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.
引用
收藏
页码:028102 / 1
页数:4
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