Multiple-pyrene residues arrayed along DNA backbone exhibit significant excimer fluorescence

被引:19
作者
Kosuge, M [1 ]
Kubota, M [1 ]
Ono, A [1 ]
机构
[1] Tokyo Metropolitan Univ, Grad Sch Sci, Dept Chem, Hachioji, Tokyo 1920397, Japan
关键词
D O I
10.1016/j.tetlet.2004.03.074
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Oligodeoxyribonuelcotides (ODNs) carrying multi-pyrene clusters were chemically prepared by introducing a novel nucleoside-pyrene conjugate into ODNs. The multi-pyrene residues arrayed on DNA strands induced significant excimer fluorescence and the intensity was exponentially increased as the number of pyrene residues in clusters increased. The excimer fluorescence of the arrays was stable and was not quenched by duplex formation. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3945 / 3947
页数:3
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