Intensity-modulated radiation therapy for prostate cancer

被引：88

作者：

Zelefsky, MJ ^{[1
]}

Fuks, Z ^{[1
]}

Leibel, SA ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, New York, NY 10021 USA

来源：

SEMINARS IN RADIATION ONCOLOGY | 2002年 / 12卷 / 03期

关键词：

D O I：

10.1053/srao.2002.00000

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Intensity-modulated radiation therapy (IMRT) represents a new paradigm in radiation treatment planning and delivery for treatment of prostate cancer with enormous potential. Preliminary data indicate that this highly conformal treatment technique can effectively reduce acute and late-occurring toxicities, improving the quality of life of the treated patient and serving as the optimal dose escalation tool. IMRT produces radiation distributions capable of delivering different dose prescriptions to multiple target sites, providing a new opportunity for differential dose painting to increase the dose selectively to specific, image-defined regions within the prostate. Clinical trials will be necessary to define more clearly the true extent of improved tumor control and reduction in normal tissue complications with IMRT in the treatment of prostate cancer. Copyright 2002, Elsevier Science (USA). All rights reserved.

引用

页码：229 / 237

页数：9

共 34 条

[1] OPTIMIZATION OF STATIONARY AND MOVING BEAM RADIATION-THERAPY TECHNIQUES [J].

BRAHME, A .

RADIOTHERAPY AND ONCOLOGY, 1988, 12 (02) :129-140

[2] Planning, delivery, and quality assurance of intensity-modulated radiotherapy using dynamic multileaf collimator: A strategy for large-scale implementation for the treatment of carcinoma of the prostate [J].

Burman, C ;

Chui, CS ;

Kutcher, G ;

Leibel, S ;

Zelefsky, M ;

LoSasso, T ;

Spirou, S ;

Wu, QW ;

Yang, J ;

Stein, J ;

Mohan, R ;

Fuks, Z ;

Ling, CC .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 39 (04) :863-873

[3] PEACOCK(TM) - A SYSTEM FOR PLANNING AND ROTATIONAL DELIVERY OF INTENSITY-MODULATED FIELDS [J].

CAROL, MP .

INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY, 1995, 6 (01) :56-61

[4]

Crook JM, 1997, CANCER-AM CANCER SOC, V79, P328, DOI 10.1002/(SICI)1097-0142(19970115)79:2<328::AID-CNCR16>3.0.CO

[5]

2-2

[6] Optimization and clinical use of multisegment intensity-modulated radiation therapy for high-dose conformal therapy [J].

Fraass, BA ;

Kessler, ML ;

McShan, DL ;

Marsh, LH ;

Watson, BA ;

Dusseau, WJ ;

Eisbruch, A ;

Sandler, HM ;

Lichter, AS .

SEMINARS IN RADIATION ONCOLOGY, 1999, 9 (01) :60-+

[7] PATTERNS OF CARE AND RTOG STUDIES IN PROSTATE-CANCER - LONG-TERM SURVIVAL, HAZARD RATE OBSERVATIONS, AND POSSIBILITIES OF CURE [J].

HANKS, GE ;

KRALL, JM ;

HANLON, AL ;

ASBELL, SO ;

PILEPICH, MV ;

OWEN, JB .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1994, 28 (01) :39-45

[8] Dose selection for prostate cancer patients based on dose comparison and dose response studies [J].

Hanks, GE ;

Hanlon, AL ;

Pinover, WH ;

Horwitz, EM ;

Price, RA ;

Schultheiss, T .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2000, 46 (04) :823-832

[9] Late rectal bleeding after conformal radiotherapy of prostate cancer (II): Volume effects and dose-volume histograms [J].

Jackson, A ;

Skwarchuk, MW ;

Zelefsky, MJ ;

Cowen, DM ;

Venkatraman, ES ;

Levegrun, S ;

Burman, CM ;

Kutcher, GJ ;

Fuks, Z ;

Liebel, SA ;

Ling, CC .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 49 (03) :685-698

[10] Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.1-cm(3)) spatial resolution [J].

Kurhanewicz, J ;

Vigneron, DB ;

Hricak, H ;

Narayan, P ;

Carroll, P ;

Nelson, SJ .

RADIOLOGY, 1996, 198 (03) :795-805

← 1 2 3 4 →