Collectins and innate immunity in the lung

被引:28
作者
Clark, HW [1 ]
Reid, KBM [1 ]
Sim, RB [1 ]
机构
[1] Univ Oxford, Dept Biochem, MRC, Immunochem Unit, Oxford OX1 3QU, England
基金
英国医学研究理事会;
关键词
innate immunity; collectin; lung surfactant; infectious disease;
D O I
10.1016/S1286-4579(00)00301-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Evidence from both in vitro and in vivo studies suggests that the collectins are important elements in host innate immune defences against infectious agents. Study of the collectins in specific disease settings now raises the prospects of developing therapies exploiting these mechanisms of innate immunity. (C) 2000 Editions scientifiques er medicales Elsevier SAS.
引用
收藏
页码:273 / 278
页数:6
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