From placode to polarization: new tunes in inner ear development

被引：175

作者：

Barald, KF

Kelley, MW ^{[1
]}

机构：

[1] Natl Inst Deafness & Other Communicat Disorders, Sect Dev Neurosci, NIH, Rockville, MD 20850 USA

[2] Univ Michigan, Cell & Mol Biol Program, Dept Cell & Dev Biol, Sch Med, Ann Arbor, MI 48109 USA

来源：

DEVELOPMENT | 2004年 / 131卷 / 17期

关键词：

D O I：

10.1242/dev.01339

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The highly orchestrated processes that generate the vertebrate inner ear from the otic placode provide an excellent and circumscribed testing ground for fundamental cellular and molecular mechanisms of development. The recent pace of discovery in developmental auditory biology has been unusually rapid, with hundreds of papers published in the past 4 years. This review summarizes studies addressing several key issues that shape our current thinking about inner ear development, with particular emphasis on early patterning events, sensory hair cell specification and planar cell polarity.

引用

页码：4119 / 4130

页数：12

共 112 条

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