Tris(cyclohexylcarbamate)s of cellulose and amylose as potential chiral stationary phases for high-performance liquid chromatography and thin-layer chromatography

被引：62

作者：

Kubota, T ^{[1
]}

Yamamoto, C ^{[1
]}

Okamoto, Y ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Engn, Dept Appl Chem, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 17期

关键词：

D O I：

10.1021/ja992421q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cyclohexylcarbamates of cellulose and amylose were prepared and their resolving abilities for enantiomers were evaluated as chiral stationary phases (CSPs) for high-performance liquid chromatography. The CSPs showed high resolving abilities, which are comparable to those of popular CSPs, tris(3,5-dmethylphenylcarbamate)s of cellulose and amylose. The cycloalkylcarbamates could also be used as CSPs for thin-layer chromatography because of the absence of a phenyl group, which causes the difficulty of detection by UV radiation. In addition, these two derivatives were soluble in chloroform and exhibited chiral discrimination to some chiral compounds in H-1 NMR spectroscopy as well as in HPLC.

引用

页码：4056 / 4059

页数：4

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