Phenanthridinium as an artificial base and charge donor in DNA

被引：51

作者：

Amann, N ^{[1
]}

Huber, R ^{[1
]}

Wagenknecht, HA ^{[1
]}

机构：

[1] Tech Univ Munich, Inst Organ Chem & Biochem, D-85747 Garching, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 14期

关键词：

DNA; electron transfer; ethidium ion; fluorescence spectroscopy; oligonucleotides;

D O I：

10.1002/anie.200353153

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A tool for time-resolved studies: The phenanthridinium unit of ethidium was incorporated into oligonucleotides (see scheme) as an artificial DNA base. The resulting duplexes can be used to study electron-transfer processes by spectroscopic techniques and to compare the rates of reductive electron transfer and oxidative hole transfer.

引用

页码：1845 / 1847

页数：3

共 32 条

[1] Synthesis of an ethidium nucleoside and its acyclic analog [J].

Amann, N ;

Wagenknecht, HA .

TETRAHEDRON LETTERS, 2003, 44 (08) :1685-1690

[2]

AMANN N, UNPUB

[3] PHOTOINDUCED ELECTRON-TRANSFER REACTIONS BETWEEN COPPER IONS AND ETHIDIUM-BROMIDE IN POLYNUCLEOTIDES [J].

ATHERTON, SJ ;

BEAUMONT, PC .

JOURNAL OF PHYSICAL CHEMISTRY, 1995, 99 (31) :12025-12029

[4] LASER FLASH-PHOTOLYSIS OF DNA-INTERCALATED ETHIDIUM-BROMIDE IN THE PRESENCE OF METHYLVIOLOGEN [J].

ATHERTON, SJ ;

BEAUMONT, PC .

JOURNAL OF PHYSICAL CHEMISTRY, 1987, 91 (15) :3993-3997

[5] Amide group assisted 3′-dephosphorylation of oligonucleotides synthesized on universal A-supports [J].

Azhayev, AV ;

Antopolsky, ML .

TETRAHEDRON, 2001, 57 (23) :4977-4986

[6] DYNAMICS OF ELECTRON-TRANSFER BETWEEN INTERCALATED POLYCYCLIC MOLECULES - EFFECT OF INTERSPERSED BASES [J].

BRUN, AM ;

HARRIMAN, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (10) :3656-3660

[7]

Cosa G, 2001, PHOTOCHEM PHOTOBIOL, V73, P585, DOI 10.1562/0031-8655(2001)073<0585:PPOFDD>2.0.CO

[8]

[9] BASE-SELECTIVE OXIDATION AND CLEAVAGE OF DNA BY PHOTOCHEMICAL COSENSITIZED ELECTRON-TRANSFER [J].

DUNN, DA ;

LIN, VH ;

KOCHEVAR, IE .

BIOCHEMISTRY, 1992, 31 (46) :11620-11625

[10] PHOTOINDUCED ELECTRON-TRANSFER IN DNA MATRIX FROM INTERCALATED ETHIDIUM TO CONDENSED METHYLVIOLOGEN [J].

FROMHERZ, P ;

RIEGER, B .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (17) :5361-5362

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