One-pot and catalyst-free synthesis of thiosemicarbazones via multicomponent coupling reactions

被引：28

作者：

Cunha, Silvio ^{[1
]}

da Silva, Tiago Lima ^{[1
]}

机构：

[1] Univ Fed Bahia, Inst Quim, BR-40170290 Salvador, BA, Brazil

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 18期

关键词：

Thiosemicarbazones; Three-component reactions; DIVERSITY-ORIENTED SYNTHESIS; SEMICARBAZONES; CHEMISTRY;

D O I：

10.1016/j.tetlet.2009.02.134

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

A novel and efficient procedure for the synthesis of thiosemicarbazones has been achieved via a multi-component and catalyst-free reaction of phenyl or p-chlorophenyl isothiocyanate, hydrazine, and aldehydes or ketones. The method afforded 20 thiosemicarbazones in good yields and short reaction time. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2090 / 2093

页数：4

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