Remarkable 4,4′-substituent effects on binap:: Highly enantioselective Ru catalysts for asymmetric hydrogenation of β-aryl ketoesters and their immobilization in room-temperature ionic liquids

被引：127

作者：

Hu, AG ^{[1
]}

Ngo, HL ^{[1
]}

Lin, WB ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 19期

关键词：

asymmetric catalysis; chirality; hydrogenation; ionic liquids; phosphanes; ruthenium;

D O I：

10.1002/anie.200353415

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A family of chiral diphosphanes with systematically tunable electronic and steric properties have been used in the asymmetric hydrogenation of β-aryl ketoesters with excellent ee values (up to 99.8%) by taking advantage of remarkable 4,4′-substituent effects on binap. These highly enantioselective Ru catalysts have also been effectively immobilized in room-temperature ionic liquids (RTIL).

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页码：2501 / 2504

页数：4

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