Regulatory RNAs in Bacteria

被引：1195

作者：

Waters, Lauren S. ^{[1
]}

Storz, Gisela ^{[1
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Cell Biol & Metab Program, Bethesda, MD 20892 USA

来源：

CELL | 2009年 / 136卷 / 04期

关键词：

SMALL NONCODING RNAS; PROVIDES ACQUIRED-RESISTANCE; SOS-INDUCED TOXIN; MESSENGER-RNA; ESCHERICHIA-COLI; GENE-EXPRESSION; 6S RNA; DEPENDENT REGULATION; PROTEIN-SYNTHESIS; GLMS EXPRESSION;

D O I：

10.1016/j.cell.2009.01.043

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacteria possess numerous and diverse means of gene regulation using RNA molecules, including mRNA leaders that affect expression in cis, small RNAs that bind to proteins or base pair with target RNAs, and CRISPR RNAs that inhibit the uptake of foreign DNA. Although examples of RNA regulators have been known for decades in bacteria, we are only now coming to a full appreciation of their importance and prevalence. Here, we review the known mechanisms and roles of regulatory RNAs, highlight emerging themes, and discuss remaining questions.

引用

页码：615 / 628

页数：14

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