A nitric oxide biosensor based on the photovoltaic effect of nano titanium dioxide on hemoglobin

被引:6
作者
Huang, J. Y. [1 ,2 ]
Liu, Y. X. [1 ,2 ]
Liu, T. [3 ,4 ]
Gan, X. [3 ,4 ]
Liu, X. J. [3 ,4 ]
机构
[1] Shanghai Univ, Sch Life Sci, Shanghai 200444, Peoples R China
[2] Shanghai Univ, Shanghai Key Lab Bioenergy Crops, Shanghai 200444, Peoples R China
[3] Nanjing Univ, Dept Biochem, Nanjing 21009, Peoples R China
[4] Nanjing Univ, Natl Key Lab Pharmaceut Biotechnol, Nanjing 21009, Peoples R China
基金
中国国家自然科学基金;
关键词
ELECTRON-TRANSFER; L-ARGININE; FILMS; NANOPARTICLES; NANO-TIO2; DNA;
D O I
10.1134/S1061934809070132
中图分类号
O65 [分析化学];
学科分类号
070302 [分析化学];
摘要
A nitric oxide biosensor based on the photovoltaic effect of nano titanium dioxide on hemoglobin was fabricated with high sensitivity, selectivity, as well as stability. The linear detection concentration range was 5.0 x 10(-6)-4.0 x 10(-4) M. The detection limit was 1.0 x 10(-6) M with a sensitivity of 8 nA/mu M. The possible coexisting compounds would not interfere with the nitric oxide detection.
引用
收藏
页码:735 / 737
页数:3
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