Ideas of order for amyloid fibril structure

被引：119

作者：

Wetzel, R ^{[1
]}

机构：

[1] Univ Tennessee, Med Ctr, Grad Sch Med, Knoxville, TN 37920 USA

来源：

STRUCTURE | 2002年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0969-2126(02)00809-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although we know a significant amount about amyloid structure from low-resolution methods, the nature of the fundamental amyloid fibril folding motif remains unknown. Recent data are keeping one model, based on the parallel β helix, in the foreground of speculation on the molecular make-up of amyloid.

引用

页码：1031 / 1036

页数：6

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