Halorhodopsin: light-driven ion pumping made simple?

被引:84
作者
Essen, LO [1 ]
机构
[1] Univ Marburg, Dept Chem, D-35032 Marburg, Germany
关键词
D O I
10.1016/S0959-440X(02)00356-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Halorhodopsin, a light-driven halide pump, is the second archaeal rhodopsin involved in ion pumping to be studied at high resolution by X-ray crystallography, Like its cousin bacteriorhodopsin, halorhodopsin couples vectorial ion transport to the isomerisation state of a covalently linked retinal. Given the similarity and interconvertability of these two ion pumps, a unified mechanism for ion translocation by archaeal rhodopsins is now emerging.
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页码:516 / 522
页数:7
相关论文
共 52 条
[1]   LIGHT-DRIVEN PROTON OR CHLORIDE PUMPING BY HALORHODOPSIN [J].
BAMBERG, E ;
TITTOR, J ;
OESTERHELT, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) :639-643
[2]  
BESIR H, 2001, THESIS L MAXIMILIANS
[3]   Interaction of proton and chloride transfer pathways in recombinant bacteriorhodopsin with chloride transport activity: Implications for the chloride translocation mechanism [J].
Brown, LS ;
Needleman, R ;
Lanyi, JK .
BIOCHEMISTRY, 1996, 35 (50) :16048-16054
[4]   Crystallization in cubo:: general applicability to membrane proteins [J].
Chiu, ML ;
Nollert, P ;
Loewen, MC ;
Belrhali, H ;
Pebay-Peyroula, E ;
Rosenbusch, JP ;
Landau, EM .
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2000, 56 :781-784
[5]   Temperature and halide dependence of the photocycle of halorhodopsin from Natronobacterium pharaonis [J].
Chizhov, I ;
Engelhard, M .
BIOPHYSICAL JOURNAL, 2001, 81 (03) :1600-1612
[6]   Existence of two L photointermediates of halorhodopsin from Halobacterium salinarum, differing in their protein and water FTIR bands [J].
Chon, YS ;
Kandori, H ;
Sasaki, J ;
Lanyi, JK ;
Needleman, R ;
Maeda, A .
BIOCHEMISTRY, 1999, 38 (29) :9449-9455
[7]   Palmitic acid is associated with halorhodopsin as a free fatty acid Radiolabeling of halorhodopsin with 3H-palmitic acid and chemical analysis of the reaction products of purified halorhodopsin with thiols and NaBH4 [J].
Colella, M ;
Lobasso, S ;
Babudri, F ;
Corcelli, A .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1998, 1370 (02) :273-279
[8]   Role of palmitic acid on the isolation and properties of halorhodopsin [J].
Corcelli, A ;
Lobasso, S ;
Colella, M ;
Trotta, M ;
Guerrieri, A ;
Palmisano, F .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1996, 1281 (02) :173-181
[9]   X-ray structure of a CIC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity [J].
Dutzler, R ;
Campbell, EB ;
Cadene, M ;
Chait, BT ;
MacKinnon, R .
NATURE, 2002, 415 (6869) :287-294
[10]   Early structural rearrangements in the photocycle of an integral membrane sensory receptor [J].
Edman, K ;
Royant, A ;
Nollert, P ;
Maxwell, CA ;
Pebay-Peyroula, E ;
Navarro, J ;
Neutze, R ;
Landau, EM .
STRUCTURE, 2002, 10 (04) :473-482