Determination of the regio- and enantioselectivity of the enzymatic hydrolyses of succinates based on H,C COLOC analysis and deuterium NMR in a chiral liquid crystal

被引：8

作者：

Chevtchouk, T

Ollivier, J

Salaun, J

Merlet, D

Courtieu, J

机构：

[1] UNIV PARIS 11,INST CHIM MOL,LAB CARBOCYCLES,F-91405 ORSAY,FRANCE

[2] UNIV PARIS 11,INST CHIM MOL,LAB CHIM STRUCT ORGAN,F-91405 ORSAY,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(97)00075-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The regio- and enantiomeric excess analyses of (S)-half esters resulting from enzymatic (lipase, esterase) hydrolyses of chiral dimethyl succinates, were accurately determined from H,C COLOC experiments and H-2 NMR in liquid crystal (PBLG, CH2Cl2). (C) 1997 Elsevier Science Ltd.

引用

收藏

页码：999 / 1003

页数：5

相关论文

共 25 条

[1] REGIOSELECTIVE PALLADIUM(0) CATALYZED AZIDATION AND AMINATION OF 1-ALKENYLCYCLOPROPYL ESTERS - A NEW ROUTE TO 2,3-METHANOAMINO ACIDS [J].

AUFRANC, P ;

OLLIVIER, J ;

STOLLE, A ;

BREMER, C ;

ESSAYED, M ;

DEMEIJERE, A ;

SALAUN, J .

TETRAHEDRON LETTERS, 1993, 34 (26) :4193-4196

[2] PREPARATION OF (R)-VERATRYL-SUCCINATES AND (R)-(3-METHOXYBENZYL)SUCCINATES [J].

BARNIER, JP ;

BLANCO, L ;

GUIBEJAMPEL, E ;

ROUSSEAU, G .

TETRAHEDRON, 1989, 45 (16) :5051-5058

[3]

BAYLE JP, 1992, NEW J CHEM, V16, P837

[4] PROTON-TRANSFER STEPS IN STEGLICH ESTERIFICATION - A VERY PRACTICAL NEW METHOD FOR MACROLACTONIZATION [J].

BODEN, EP ;

KECK, GE .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (13) :2394-2395

[5] NEW, AND ACCURATE METHOD TO DETERMINE THE ENANTIOMERIC PURITY OF AMINO-ACIDS BASED ON DEUTERIUM NMR IN A CHOLESTERIC LYOTROPIC LIQUID-CRYSTAL [J].

CANET, I ;

MEDDOUR, A ;

COURTIEU, J ;

CANET, JL ;

SALAUN, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (05) :2155-2156

[6] ENANTIOMERIC ANALYSIS IN A POLYPEPTIDE LYOTROPIC LIQUID-CRYSTAL BY DEUTERIUM NMR [J].

CANET, I ;

COURTIEU, J ;

LOEWENSTEIN, A ;

MEDDOUR, A ;

PECHINE, JM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (24) :6520-6526

[7] ENANTIOMERIC EXCESS ANALYSIS OF SESQUITERPENE PRECURSORS THROUGH PROTON DECOUPLED DEUTERIUM NMR IN CHOLESTERIC LYOTROPIC LIQUID-CRYSTAL [J].

CANET, JL ;

FADEL, A ;

SALAUN, J ;

CANETFRESSE, I ;

COURTIEU, J .

TETRAHEDRON-ASYMMETRY, 1993, 4 (01) :31-34

[8]

CHETCHOUK T, 1997, TETAHEDRON ASYMMETRY, V8, P1011

[9] OPTICALLY-ACTIVE ALPHA-ALKYLSUCCINATES FROM THE STEREOSELECTIVE ALKYLATION OF CHIRAL IMIDE ENOLATES [J].

FADEL, A ;

SALAUN, J .

TETRAHEDRON LETTERS, 1988, 29 (48) :6257-6260

[10]

FRAZER RR, 1971, J CHEM SOC CHEM COMM, V22, P1450