Hydrodynamics of nanoscopic tubulin rings in dilute solutions

被引：18

作者：

Boukari, H ^{[1
]}

Nossal, R

Sackett, DL

Schuck, P

机构：

[1] NICHD, Lab Integrat & Med Biophys, Bethesda, MD 20892 USA

[2] NIH, Div Bioengn & Phys Sci, ORS OD, Bethesda, MD 20892 USA

来源：

PHYSICAL REVIEW LETTERS | 2004年 / 93卷 / 09期

关键词：

D O I：

10.1103/PhysRevLett.93.098106

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We combine fluorescence correlation spectroscopy and sedimentation velocity measurements to probe the hydrodynamic behavior of tubulin dimers and nanoscopic tubulin rings. The rings are rigid, have circular geometry, and are monodisperse in size. We use the high-precision ratio of the sedimentation coefficients and that of the translational diffusion coefficients to validate theories for calculating the hydrodynamic properties of supramolecular structures.

引用

页码：098106 / 1

页数：4

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