Inorganic-biomolecular hybrid nanomaterials as a genetic molecular code system

被引:102
作者
Choy, JH [1 ]
Oh, JM
Park, M
Sohn, KM
Kim, JW
机构
[1] Seoul Natl Univ, Sch Chem & Mol Engn, NNML, Seoul 151747, South Korea
[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Lab Med, Seoul 135710, South Korea
关键词
D O I
10.1002/adma.200400027
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
A molecular-level coding method utilizing DNA base pairs as code units has been systemized. The system consists of four steps: encoding, encrypting, decrypting and decoding (see Figure), which are realized by tailor-made nanohybrids (DNA-layered double hydroxide (LDH) and polypyrrole-maghemite). The nanohybrids give solutions to the inherent problems which hamper DNA molecular code systems; stability in encrypting and rapidity in analysis.
引用
收藏
页码:1181 / +
页数:5
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