Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?

被引:234
作者
Mueller, Ingrid [2 ]
Munder, Markus [1 ,3 ]
Kropf, Pascale [2 ]
Haensch, Gertrud Maria [1 ]
机构
[1] Heidelberg Univ, Inst Immunol, D-69120 Heidelberg, Germany
[2] Univ London Imperial Coll Sci Technol & Med, Fac Med, Dept Immunol, London W2 1PG, England
[3] Heidelberg Univ, Dept Hematol Oncol & Rheumatol, D-69120 Heidelberg, Germany
关键词
NITRIC-OXIDE SYNTHASE; RENAL-CELL CARCINOMA; SUPPRESSOR-CELLS; CLASS-II; PERIPHERAL-BLOOD; ARGINASE-I; RHEUMATOID-ARTHRITIS; GRANULOCYTE; ACTIVATION; EXPRESSION;
D O I
10.1016/j.it.2009.07.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Polymorphonuclear neutrophils (PMN) are linked invariably to the innate immune response, particularly to the defence against bacterial infection. T lymphocytes are studied mainly in virus infections, the defence against tumours, the development and progression of chronic inflammatory processes, in autoimmune phenomena and in materno-fetal tolerance. There is, however, increasing evidence for communication and interactions between PMN and T cells that we discuss here in the context of different physiological and pathological conditions, including acute and chronic inflammatory disease, defence against tumours, and maintenance of pregnancy.
引用
收藏
页码:522 / 530
页数:9
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