Heterogeneous palladium multi-task catalyst for sequential Heck-reduction-cyclization (HRC) reactions: influence of the support

被引：48

作者：

Ibarguren, Oier ^{[1
]}

Zakri, Cecile ^{[2
]}

Fouquet, Eric ^{[1
]}

Felpin, Francois-Xavier ^{[1
]}

机构：

[1] Univ Bordeaux, CNRS, Inst Mol Sci, F-33405 Talence, France

[2] Univ Bordeaux, CNRS, Ctr Rech Paul Pascal, F-33600 Pessac, France

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 36期

关键词：

Heterogeneous palladium catalysis; Aryldiazonium tetrafluoroborate salts; Heck reaction; Sustainable chemistry; One-pot reactions; ONE-POT SYNTHESIS; SALTS; EFFICIENT; TETRAFLUOROBORATE; SYSTEMS; CARBON;

D O I：

10.1016/j.tetlet.2009.06.084

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An evaluation study of various palladium supports led to the selection of charcoal as the most efficient system for the preparation of oxindoles by sequential Heck-reduction-cyclization (HRC) reactions. The in situ prepared Pd0/C was not recyclable for further cross-coupling reactions but remains still highly active for reduction processes. The sustainable chemistry described herein allows extremely simple experimental protocol Under mild conditions, free of any base, ligand and additive. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：5071 / 5074

页数：4

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