Allylpalladium umpolung in the three-component coupling synthesis of homoallylic amines

被引：32

作者：

Hopkins, Chad D. ^{[1
]}

Malinakova, Helena C. ^{[1
]}

机构：

[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 26期

关键词：

D O I：

10.1021/ol0624528

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Homoallylic amines and alpha-amino esters were prepared via a Pd(II)-catalyzed coupling of boronic acids and 1,2- nonadiene with ethyl iminoacetate or aliphatic, aromatic, and heteroaromatic imines. The allylpalladium umpolung was induced by a Pd( OAc)(2) catalyst with commercial phosphine ligands.

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页码：5971 / 5974

页数：4

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