Postnatal growth and circulating ACTH and cortisol concentrations during the first month of life in cloned lambs

被引：7

作者：

Edwards, L ^{[1
]}

Peura, T

Hartwich, K

Rudiger, S

McMillen, IC

Walker, S

机构：

[1] Univ Adelaide, Dept Physiol, Adelaide, SA 5005, Australia

[2] S Australian Res & Dev Inst, Turretfield Res Ctr, Rosedale, SA 5350, Australia

来源：

ENDOCRINOLOGY | 2002年 / 143卷 / 09期

关键词：

D O I：

10.1210/en.2002-220500

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent studies have indicated that there is a decrease in perinatal survival of apparently normal animals produced by somatic-cell nuclear transfer. Here we report that the cortisol and adrenocorticotrophic hormone (ACTH) profiles of cloned lambs in the first 4 weeks of life are significantly different to that of control lambs. The growth of cloned lambs however was not different to controls. These findings demonstrate that endocrine development may be altered in apparently "normal" clones.

引用

页码：3699 / 3702

页数：4

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