Efficacy of platelet-rich plasma in alveolar bone grafting

被引：123

作者：

Oyama, T ^{[1
]}

Nishimoto, S ^{[1
]}

Tsugawa, T ^{[1
]}

Shimizu, F ^{[1
]}

机构：

[1] Kobe Childrens Hosp, Dept Plast Surg, Suma Ku, Kobe, Hyogo 6540081, Japan

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2004年 / 62卷 / 05期

关键词：

D O I：

10.1016/j.joms.2003.08.023

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Purpose: In this study, we performed alveolar bone grafting with autologous iliac cancellous bone incorporation with platelet-rich plasma (PRP) and evaluated its efficacy in osteoregeneration. Materials and Methods: Seven alveolar cleft patients with adult dentition (average age, 16.1 years) underwent iliac bone grafting with PRP. Quantitative evaluation of regenerated bone was made with 3-dimensional computed tomography scans and compared with controls. Results: The average of the volume ratio of regenerated bone to alveolar cleft in cases with PRP was higher than in controls (P < .05). There were no complications from the blood draw or PRP. Conclusion: PRP was a safe and cost-effective source for growth factors and was easy to extract. It could enhance the osteogenesis of alveolar bone grafting in cleft lip and palate patients and may useful for subsequent orthodontic therapy. (C) 2004 American Association of Oral and Maxillofacial Surgeons.

引用

页码：555 / 558

页数：4

共 22 条

[11] Alveolar ridge and sinus augmentation utilizing platelet-rich plasma in combination with freeze-dried bone allograft: Case series [J].

Kassolis, JD ;

Rosen, PS ;

Reynolds, MA .

JOURNAL OF PERIODONTOLOGY, 2000, 71 (10) :1654-1661

[12] Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation [J].

Landesberg, R ;

Roy, M ;

Glickman, RS .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2000, 58 (03) :297-300

[13] Platelet-rich plasma - Growth factor enhancement for bone grafts [J].

Marx, RE ;

Carlson, ER ;

Eichstaedt, RM ;

Schimmele, SR ;

Strauss, JE ;

Georgeff, KR .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1998, 85 (06) :638-646

[14] INDIRECT INTRACRANIAL VOLUME MEASUREMENTS USING CT SCANS - CLINICAL-APPLICATIONS FOR CRANIOSYNOSTOSIS [J].

POSNICK, JC ;

BITE, U ;

NAKANO, P ;

DAVIS, J ;

ARMSTRONG, D .

PLASTIC AND RECONSTRUCTIVE SURGERY, 1992, 89 (01) :34-45

[15] A CT scan technique for quantitative volumetric assessment of the mandible after distraction osteogenesis [J].

Roth, DA ;

Gosain, AK ;

McCarthy, JG ;

Stracher, MA ;

Lefton, DR ;

Grayson, BH .

PLASTIC AND RECONSTRUCTIVE SURGERY, 1997, 99 (05) :1237-1247

[16] The biology of platelet-rich plasma [J].

Schmitz, JP ;

Hollinger, JO .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2001, 59 (09) :1119-1120

[17] COMPARATIVE-STUDY OF SECONDARY AND LATE SECONDARY BONE-GRAFTING IN PATIENTS WITH RESIDUAL CLEFT DEFECTS - SHORT-TERM EVALUATION [J].

SINDETPEDERSEN, S ;

ENEMARK, H .

INTERNATIONAL JOURNAL OF ORAL SURGERY, 1985, 14 (05) :389-398

[18] INVOLVEMENT OF PLATELETS IN STIMULATING OSTEOGENIC ACTIVITY [J].

SLATER, M ;

PATAVA, J ;

KINGHAM, K ;

MASON, RS .

JOURNAL OF ORTHOPAEDIC RESEARCH, 1995, 13 (05) :655-663

[19]

Sonnleitner D, 2000, INT J ORAL MAX IMPL, V15, P879

[20]

Tischler Michael, 2002, N Y State Dent J, V68, P22

← 1 2 3 →