Interfacing Glycosylated Carbon-Nanotube-Network Devices with Living Cells to Detect Dynamic Secretion of Biomolecules

被引：124

作者：

Sudibya, Herry Gunadi ^{[2
]}

Ma, Jimei ^{[1
]}

Dong, Xiaochen ^{[2
]}

Ng, Simon ^{[1
]}

Li, Lain-Jong ^{[3
]}

Liu, Xue-Wei ^{[1
]}

Chen, Peng ^{[2
]}

机构：

[1] Nanyang Technol Univ, Sch Math & Phys Sci, Singapore 637371, Singapore

[2] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637457, Singapore

[3] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 637457, Singapore

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 15期

关键词：

bionanotechnology; biosensors; carbohydrates; carbon nanotubes; CARBOHYDRATE-CARBOHYDRATE INTERACTIONS; HEPARAN-SULFATE PROTEOGLYCANS; SCAFFOLDS; ADHESION; GROWTH; RECOGNITION; BIOSENSORS;

D O I：

10.1002/anie.200805514

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A sense of cell-being: Single-walled carbon nanotubes (SWNTs) are functionalized with bioactive monosaccharides to enable their use as biosensors. The glycosylated nanotube network is biocompatible and can interface with living cells (see scheme) to electronically detect biomolecular release with high temporal resolution and high sensitivity. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2723 / 2726

页数：4

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